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1

Let's see how tmRNA rescues a stuck ribosome

Klaholz, Bruno P

Journal:

The EMBO Journal

Year:

2010

Language:

english

File:

PDF, 469 KB

english, 2010

2

Structured mRNAs Regulate Translation Initiation by Binding to the Platform of the Ribosome

Stefano Marzi, Alexander G. Myasnikov, Alexander Serganov, Chantal Ehresmann, Pascale Romby, Marat Yusupov, Bruno P. Klaholz

Journal:

Year:

2007

Language:

english

File:

PDF, 1.69 MB

english, 2007

3

Structure of the human 80S ribosome

Khatter, Heena, Myasnikov, Alexander G., Natchiar, S. Kundhavai, Klaholz, Bruno P.

Journal:

Year:

2015

Language:

english

File:

PDF, 9.88 MB

english, 2015

4

Volta phase plate data collection facilitates image processing and cryo-EM structure determination

von Loeffelholz, Ottilie, Papai, Gabor, Danev, Radostin, Myasnikov, Alexander G., Kundhavai Natchiar, S., Hazemann, Isabelle, Ménétret, Jean-François, Klaholz, Bruno P.

Journal:

Journal of Structural Biology

Year:

2018

Language:

english

File:

PDF, 1.07 MB

english, 2018

5

N6-Methyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation

Ma, Honghui, Wang, Xiaoyun, Cai, Jiabin, Dai, Qing, Natchiar, S. Kundhavai, Lv, Ruitu, Chen, Kai, Lu, Zhike, Chen, Hao, Shi, Yujiang Geno, Lan, Fei, Fan, Jia, Klaholz, Bruno P., Pan, Tao, Shi, Yang, H

Journal:

Nature Chemical Biology

Year:

2019

Language:

english

File:

PDF, 1.63 MB

english, 2019

6

Structure of the Escherichia coli ribosomal termination complex with release factor 2

Klaholz, Bruno P., Pape, Tillmann, Zavialov, Andrey V., Myasnikov, Alexander G., Orlova, Elena V., Vestergaard, Bente, Ehrenberg, Måns, van Heel, Marin

Journal:

Year:

2003

Language:

english

File:

PDF, 558 KB

english, 2003

7

Visualization of release factor 3 on the ribosome during termination of protein synthesis

Klaholz, Bruno P., Myasnikov, Alexander G., van Heel, Marin

Journal:

Year:

2004

Language:

english

File:

PDF, 324 KB

english, 2004

8

Structure of the 30S translation initiation complex

Simonetti, Angelita, Marzi, Stefano, Myasnikov, Alexander G., Fabbretti, Attilio, Yusupov, Marat, Gualerzi, Claudio O., Klaholz, Bruno P.

Journal:

Year:

2008

Language:

english

File:

PDF, 715 KB

english, 2008

9

Conformational transition of initiation factor 2 from the GTP- to GDP-bound state visualized on the ribosome

Myasnikov, Alexander G, Marzi, Stefano, Simonetti, Angelita, Giuliodori, Anna Maria, Gualerzi, Claudio O, Yusupova, Gulnara, Yusupov, Marat, Klaholz, Bruno P

Journal:

Nature Structural and Molecular Biology

Year:

2005

Language:

english

File:

PDF, 583 KB

english, 2005

10

Structure of the full human RXR/VDR nuclear receptor heterodimer complex with its DR3 target DNA

Orlov, Igor, Rochel, Natacha, Moras, Dino, Klaholz, Bruno P

Journal:

The EMBO Journal

Year:

2011

Language:

english

File:

PDF, 1.18 MB

english, 2011

11

Structure–function insights into prokaryotic and eukaryotic translation initiation

Alexander G Myasnikov, Angelita Simonetti, Stefano Marzi, Bruno P Klaholz

Journal:

Current Opinion in Structural Biology

Year:

2009

Language:

english

File:

PDF, 3.53 MB

english, 2009

12

Molecular recognition and catalysis in translation termination complexes

Bruno P. Klaholz

Journal:

Trends in Biochemical Sciences

Year:

2011

Language:

english

File:

PDF, 1.51 MB

english, 2011

13

C–H···O Hydrogen Bonds in the Nuclear Receptor RARγ—a Potential Tool for Drug Selectivity

Bruno P Klaholz, Dino Moras

Journal:

Year:

2002

Language:

english

File:

PDF, 542 KB

english, 2002

14

Structural basis for isotype selectivity of the human retinoic acid nuclear receptor

Bruno P Klaholz, André Mitschler, Dino Moras

Journal:

Journal of Molecular Biology

Year:

2000

Language:

english

File:

PDF, 1.96 MB

english, 2000

15

Heterodimeric Complex of RAR and RXR Nuclear Receptor Ligand-Binding Domains: Purification, Crystallization, and Preliminary X-Ray Diffraction Analysis

William Bourguet, Virginie Andry, Carole Iltis, Bruno Klaholz, Noëlle Potier, Alain Van Dorsselaer, Pierre Chambon, Hinrich Gronemeyer, Dino Moras

Journal:

Protein Expression and Purification

Year:

2000

Language:

english

File:

PDF, 98 KB

english, 2000

16

Ligand–protein interactions in nuclear receptors of hormones

Pascal F Egea, Bruno P Klaholz, Dino Moras

Journal:

Year:

2000

Language:

english

File:

PDF, 306 KB

english, 2000

17

Single particle and molecular assembly analysis of polyribosomes by single- and double-tilt cryo electron tomography

Myasnikov, Alexander G., Afonina, Zhanna A., Klaholz, Bruno P.

Journal:

Ultramicroscopy

Year:

2013

Language:

english

File:

PDF, 1.06 MB

english, 2013

18

The molecular structure of the left-handed supra-molecular helix of eukaryotic polyribosomes

Myasnikov, Alexander G., Afonina, Zhanna A., Ménétret, Jean-François, Shirokov, Vladimir A., Spirin, Alexander S., Klaholz, Bruno P.

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 1.41 MB

english, 2014

19

The palindromic DNA-bound USP/EcR nuclear receptor adopts an asymmetric organization with allosteric domain positioning

Maletta, Massimiliano, Orlov, Igor, Roblin, Pierre, Beck, Yannick, Moras, Dino, Billas, Isabelle M. L., Klaholz, Bruno P.

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 1.33 MB

english, 2014

20

Live cell immunogold labelling of RNA polymerase II

Orlov, Igor, Schertel, Andreas, Zuber, Guy, Klaholz, Bruno, Drillien, Robert, Weiss, Etienne, Schultz, Patrick, Spehner, Danièle

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 760 KB

english, 2015

21

Structure and function insights into the NuRD chromatin remodeling complex

Torchy, Morgan P., Hamiche, Ali, Klaholz, Bruno P.

Journal:

Cellular and Molecular Life Sciences

Year:

2015

Language:

english

File:

PDF, 3.38 MB

english, 2015

22

Structure–function relationships in nuclear receptors: the facts

Moras, Dino, Billas, Isabelle M.L., Rochel, Natacha, Klaholz, Bruno P.

Journal:

Trends in Biochemical Sciences

Year:

2015

Language:

english

File:

PDF, 1.11 MB

english, 2015

23

X-ray and Cryo-electron Microscopy Structures of Monalysin Pore-forming Toxin Reveal Multimerization of the Pro-form

Leone, Philippe, Bebeacua, Cecilia, Opota, Onya, Kellenberger, Christine, Klaholz, Bruno, Orlov, Igor, Cambillau, Christian, Lemaitre, Bruno, Roussel, Alain

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 4.49 MB

english, 2015

24

Structure of the protein core of translation initiation factor 2 in apo, GTP-bound and GDP-bound forms

Simonetti, Angelita, Marzi, Stefano, Fabbretti, Attilio, Hazemann, Isabelle, Jenner, Lasse, Urzhumtsev, Alexandre, Gualerzi, Claudio O., Klaholz, Bruno P.

Journal:

Acta Crystallographica Section D Biological Crystallography

Year:

2013

Language:

english

File:

PDF, 1.73 MB

english, 2013

25

On effective and optical resolutions of diffraction data sets

Urzhumtseva, Ludmila, Klaholz, Bruno, Urzhumtsev, Alexandre

Journal:

Acta Crystallographica Section D Biological Crystallography

Year:

2013

Language:

english

File:

PDF, 1.05 MB

english, 2013

26

IBiSS, a versatile and interactive tool for integrated sequence and 3D structure analysis of large macromolecular complexes

Beinsteiner, Brice, Michalon, Jonathan, Klaholz, Bruno P.

Journal:

Year:

2015

Language:

english

File:

PDF, 899 KB

english, 2015

27

Escherichia coli Ribosomal Protein S1 Unfolds Structured mRNAs Onto the Ribosome for Active Translation Initiation

Duval, Mélodie, Korepanov, Alexey, Fuchsbauer, Olivier, Fechter, Pierre, Haller, Andrea, Fabbretti, Attilio, Choulier, Laurence, Micura, Ronald, Klaholz, Bruno P., Romby, Pascale, Springer, Mathias, M

Journal:

Year:

2013

Language:

english

File:

PDF, 1.46 MB

english, 2013

28

Rapid purification of ribosomal particles assembled on histone H4 mRNA: a new method based on mRNA–DNA chimaeras

Prongidi‑Fix, Lydia, Schaeffer, Laure, Simonetti, Angelita, Barends, Sharief, Ménétret, Jean‑François, Klaholz, Bruno P., Eriani, Gilbert, Martin, Franck

Journal:

Biochemical Journal

Year:

2013

Language:

english

File:

PDF, 733 KB

english, 2013

29

Phosphatase-Dead Myotubularin Ameliorates X-Linked Centronuclear Myopathy Phenotypes in Mice

Amoasii, Leonela, Bertazzi, Dimitri L., Tronchère, Hélène, Hnia, Karim, Chicanne, Gaëtan, Rinaldi, Bruno, Cowling, Belinda S., Ferry, Arnaud, Klaholz, Bruno, Payrastre, Bernard, Laporte, Jocelyn, Fria

Journal:

Year:

2012

Language:

english

File:

PDF, 4.23 MB

english, 2012

30

SharpViSu: integrated analysis and segmentation of super-resolution microscopy data

Andronov, Leonid, Lutz, Yves, Vonesch, Jean-Luc, Klaholz, Bruno P.

Journal:

Year:

2016

Language:

english

File:

PDF, 328 KB

english, 2016

31

Found in Translation: Collection of Original Articles on Single-Particle Reconstruction and the Structural Basis of Protein Synthesis. Frank Joachim (Ed.). World Scientific Publishing, Hackensack, NJ, 2014, 468 pages. ISBN: 978-981-4522-80-9

Klaholz, Bruno P.

Journal:

Microscopy and Microanalysis

Year:

2014

Language:

english

File:

PDF, 61 KB

english, 2014

32

Protein Delivery System Containing a Nickel-Immobilized Polymer for Multimerization of Affinity-Purified His-Tagged Proteins Enhances Cytosolic Transfer

Postupalenko, Viktoriia, Desplancq, Dominique, Orlov, Igor, Arntz, Youri, Spehner, Danièle, Mely, Yves, Klaholz, Bruno P., Schultz, Patrick, Weiss, Etienne, Zuber, Guy

Journal:

Angewandte Chemie

Year:

2015

Language:

english

File:

PDF, 3.62 MB

english, 2015

33

Protein Delivery System Containing a Nickel-Immobilized Polymer for Multimerization of Affinity-Purified His-Tagged Proteins Enhances Cytosolic Transfer

Postupalenko, Viktoriia, Desplancq, Dominique, Orlov, Igor, Arntz, Youri, Spehner, Danièle, Mely, Yves, Klaholz, Bruno P., Schultz, Patrick, Weiss, Etienne, Zuber, Guy

Journal:

Angewandte Chemie International Edition

Year:

2015

Language:

english

File:

PDF, 3.63 MB

english, 2015

34

Ribosome structure and function by single-particle cryo-EM

Matadeen, Rishi, Pape, Tillmann, Klaholz, Bruno, Patwardhan, Ardan, van Heel, Marin

Journal:

Biochemical Society Transactions

Year:

2002

Language:

english

File:

PDF, 116 KB

english, 2002

35

Structure–function insights reveal the human ribosome as a cancer target for antibiotics

Myasnikov, Alexander G., Kundhavai Natchiar, S., Nebout, Marielle, Hazemann, Isabelle, Imbert, Véronique, Khatter, Heena, Peyron, Jean-François, Klaholz, Bruno P.

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 2.57 MB

english, 2016

36

Cryo-EM study of start codon selection during archaeal translation initiation

Coureux, Pierre-Damien, Lazennec-Schurdevin, Christine, Monestier, Auriane, Larquet, Eric, Cladière, Lionel, Klaholz, Bruno P., Schmitt, Emmanuelle, Mechulam, Yves

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 2.39 MB

english, 2016

37

Ribosomal 18S rRNA base pairs with mRNA during eukaryotic translation initiation

Martin, Franck, Ménétret, Jean-François, Simonetti, Angelita, Myasnikov, Alexander G., Vicens, Quentin, Prongidi-Fix, Lydia, Natchiar, S. Kundhavai, Klaholz, Bruno P., Eriani, Gilbert

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 1.09 MB

english, 2016

38

ClusterViSu, a method for clustering of protein complexes by Voronoi tessellation in super-resolution microscopy

Andronov, Leonid, Orlov, Igor, Lutz, Yves, Vonesch, Jean-Luc, Klaholz, Bruno P.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.90 MB

english, 2016

39

The Ribosome Holds the RNA Polymerase on Track in Bacteria

Klaholz, Bruno P.

Journal:

Trends in Biochemical Sciences

Year:

2017

Language:

english

File:

PDF, 1.54 MB

english, 2017

40

Focused classification and refinement in high-resolution cryo-EM structural analysis of ribosome complexes

von Loeffelholz, Ottilie, Natchiar, S Kundhavai, Djabeur, Nadia, Myasnikov, Alexander G, Kratzat, Hanna, Ménétret, Jean-François, Hazemann, Isabelle, Klaholz, Bruno P

Journal:

Current Opinion in Structural Biology

Year:

2017

Language:

english

File:

PDF, 2.22 MB

english, 2017

41

Visualization of chemical modifications in the human 80S ribosome structure

Natchiar, S. Kundhavai, Myasnikov, Alexander G., Kratzat, Hanna, Hazemann, Isabelle, Klaholz, Bruno P.

Journal:

Year:

2017

Language:

english

File:

PDF, 33.19 MB

english, 2017

42

Structural features of the salivary gland hypertrophy virus of the tsetse fly revealed by cryo-electron microscopy and tomography

Orlov, Igor, Drillien, Robert, Spehner, Danièle, Bergoin, Max, Abd-Alla, Adly M.M., Klaholz, Bruno P.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.29 MB

english, 2018

43

3DClusterViSu: 3D clustering analysis of super-resolution microscopy data by 3D Voronoi tessellations

Andronov, Leonid, Michalon, Jonathan, Ouararhni, Khalid, Orlov, Igor, Hamiche, Ali, Vonesch, Jean-Luc, Klaholz, Bruno P

Journal:

Year:

2018

Language:

english

File:

PDF, 3.13 MB

english, 2018

44

Importance of the Sequence-Directed DNA Shape for Specific Binding Site Recognition by the Estrogen-Related Receptor

Mohideen-Abdul, Kareem, Tazibt, Karima, Bourguet, Maxime, Hazemann, Isabelle, Lebars, Isabelle, Takacs, Maria, Cianférani, Sarah, Klaholz, Bruno P., Moras, Dino, Billas, Isabelle M. L.

Journal:

Frontiers in Endocrinology

Year:

2017

Language:

english

File:

PDF, 2.83 MB

english, 2017

45

Tetracyclines Modify Translation by Targeting Key Human rRNA Substructures

Mortison, Jonathan D., Schenone, Monica, Myers, Jacob A., Zhang, Ziyang, Chen, Linfeng, Ciarlo, Christie, Comer, Eamon, Natchiar, S. Kundhavai, Carr, Steven A., Klaholz, Bruno P., Myers, Andrew G.

Journal:

Cell Chemical Biology

Year:

2018

Language:

english

File:

PDF, 6.76 MB

english, 2018

46

Visualizing the Role of 2’-OH rRNA Methylations in the Human Ribosome Structure

Natchiar, S., Myasnikov, Alexander, Hazemann, Isabelle, Klaholz, Bruno

Journal:

Year:

2018

Language:

english

File:

PDF, 1.26 MB

english, 2018

47

Publisher Correction: N6-Methyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation

Ma, Honghui, Wang, Xiaoyun, Cai, Jiabin, Dai, Qing, Natchiar, S. Kundhavai, Lv, Ruitu, Chen, Kai, Lu, Zhike, Chen, Hao, Shi, Yujiang Geno, Lan, Fei, Fan, Jia, Klaholz, Bruno P., Pan, Tao, Shi, Yang, H

Journal:

Nature Chemical Biology

Year:

2019

File:

PDF, 508 KB

2019

48

Publisher Correction: N6-Methyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation

Ma, Honghui, Wang, Xiaoyun, Cai, Jiabin, Dai, Qing, Natchiar, S. Kundhavai, Lv, Ruitu, Chen, Kai, Lu, Zhike, Chen, Hao, Shi, Yujiang Geno, Lan, Fei, Fan, Jia, Klaholz, Bruno P., Pan, Tao, Shi, Yang, H

Journal:

Nature Chemical Biology

Year:

2019

File:

PDF, 508 KB

2019

49

CENP-A nucleosome clusters form rosette-like structures around HJURP during G1

Andronov, Leonid, Ouararhni, Khalid, Stoll, Isabelle, Klaholz, Bruno P., Hamiche, Ali

Journal:

Nature Communications

Year:

2019

Language:

english

File:

PDF, 2.54 MB

english, 2019

50

Targeting the Human 80S Ribosome in Cancer: From Structure to Function and Drug Design for Innovative Adjuvant Therapeutic Strategies

Gilles, Arnaud, Frechin, LÃ©o, Natchiar, Kundhavai, Biondani, Giulia, Loeffelholz, Ottilie von, Holvec, Samuel, Malaval, Julie-Lisa, Winum, Jean-Yves, Klaholz, Bruno P., Peyron, Jean-FranÃ§ois

Journal:

Year:

2020

File:

PDF, 1.13 MB

2020